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Pp. 441-459, Academic Press, New York. Tannhauser, S. , 1950, Lipoidoses, Oxford Press, New York. Tannhauser, S. , New York, p. 455. Volk, B. , and Aronson, S. , 1972, "Sphingolipids, Sphingolipidoses and Allied Disorders", Plenum Press, New York/London. Weinreb, N. , Brady, R. , and Tappel, A. , 1968, The lysosomal localization of sphingolipid hydrolases, Biochim. Biophys. Acta, 159:141. Williamson, R. , 1981-1984, "Genetic Engineering", Vois. 1-4, Academic Press, New York. 17 THE MOLECULAR BIOLOGY OF GAUCHER DISEASE E.

J. Hum. Genet. In Press (1987). E. M. G. , Raven Press, New York (1979). G. M. G. , New York (1979). H. H. G. Phillips, S. Aronis, G. A. E. Antonarakis, Recurrent mutations in haemophilia A give evidence for CpG mutation hotspots, Nature 324:380 (1986). S. Huang, C. E. Antonarakis, T. Y. , The same "TATA" box beta-thalassemia mutation in Chinese and US blacks: another example of independent origins of mutation, Hum. Genet. 74:162 (1986). F. R. W. Kan, Spontaneous mutation in betathalassaemia producing the same nucleotide substitution as that in a common hereditary form, Lancet 1:3 (1986).

F. R. W. Kan, Spontaneous mutation in betathalassaemia producing the same nucleotide substitution as that in a common hereditary form, Lancet 1:3 (1986). H. Hogeboom, Fractionation of cell components of animal tissues, Methods Enzymol. 1:16 (1955). A. Gravel, and A. Leung, Complementation analysis in Gaucher disease using single cell microassay techniques. Evidence for a single "Gaucher gene", Hum. Genet. 65:112 (1983). K. Zaitsu, and Y. Ohkura, New fluorogenic substrates for horseradish peroxidase: Rapid and sensitive assays for hydrogen peroxide and the peroxidase, Anal.

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